It is recommended that each rider personally or professionally fit themselves to their bicycle.
A road bike fit consists of insuring that:

a) There is proper leg extension between the saddle and the pedals. (Do this by having a friend steady your bike, or mount your bike in a stationary trainer with the wheels level. Then place your heels on the pedals and adjust the saddle height so that your legs are fully extended on the downstroke, yet your hips don't rock as you pedal.)

b) The horizontal tilt of the saddle fits your riding style and integrates with the other fit factors. (You're going to feel different pressure depending on where you're resting on the handlebars. Adjust the tilt to be most comfortable in the position that you ride most.)

c) The distance between the saddle and the handlebars is proper. (Check this by placing your hands on the brake hoods and looking down through the center of the handlebar which should obscure the front hub. If the handlebar is ahead of the hub, you are more aerodynamic, and if it's behind, you should be more comfortable. Adjust bar reach by moving saddle forward or back and/or swapping stems. If you weigh over 250 pounds, you must attach the seat post clamp at least 1 inch from the most forward position on the frame. See below.)

d) The height of the handlebars in relation to the saddle provides for the proper angle to minimize shoulder and arm stress. (Set the handlebars lower than saddle height to be more aerodynamic(Very hard to do with any noseless saddle) , and level with or higher than saddle height to be more comfortable.)

Mountain bike: Fit considerations vary for (c) and (d) above. For (c), if the bar is ahead, it's better for climbing; if it's behind, it's better for descending. For (d), having the handlebar higher will assist with technical descents.

Exercise bike: Most exercise bicycles do not allow you to adjust anything other than saddle height. If you can adjust more handlebar distance and height, do so using the guide above.

Bicyclists should understand that it may take 100 miles or more to determine if the saddle can work for you and to arrive at optimal settings.

Riders should mount their bicycles on a bicycle trainer for initial saddle adjustment.

Riders should initially set the surfaces to the suggested starting positions.

During the adjustment process, move one or both sides, in the front or back, in increments of one-eighth inch. These adjustments can be made in or out, depending on how the rider feels. The goal is to achieve the most comfortable placement of the surfaces (NOT necessarily directly under the bones). Another goal is to have your weight spread on both the V bones (ischiopubic rami) and the knobs at the ends of the V (ischial tuberosities). Some customers have called the proper feeling "cup-your-bones". Be open to being asymmetrical.

Minor adjustments are expected during subsequent riding sessions to maximize comfort.

It is suggested, at least during the initial fitting of the saddle, that the rider eliminate all forms of padding from their shorts. This will help the rider feel most clearly the positioning of the surfaces under their ischiopubic rami and ischial tuberosities. The design intent of the surface material and hardness of the BiSaddle™ saddles was to eliminate the need for padded shorts, but some riders prefer padded shorts once the saddle is fit to their bone structure.

Suggested rotation of the saddle is 5 to 15 degrees down from level in the back.

As you rotate the saddle backwards, be aware that you may need to adjust the saddle height to maintain proper leg extension. The variations in the saddle rotation, placement of the saddle over the pedals and distance from the saddle to the handlebars affect what leg muscles are utilized most and how comfortable your neck, shoulders, arms, and posterior are.

The ability to adjust both the front and back of the BiSaddle™ saddle should embrace all pelvic variations. Adjusting the saddle to fit you most comfortably is only part of the overall bike fit equation. Leg extension, rotational angle of the saddle, height of the handlebars and the distance from the handlebars to the saddle for each person is individual.

Each BiSaddle® rider needs to take ultimate responsibility for saddle adjustment and overall bicycle fit.

If you have questions or feel that the saddle should be more comfortable, please contact us or seek professional fitting assistance. Experience has shown that, for women, the angle of the surfaces may be less than the 80 to 90 degree setting to provide proper comfort. The surfaces can be adjusted anywhere along the slot positions in the front and then within a range of 45-degrees of rotation in the back. This should provide most men and women riders with a combination of surface adjustments that works well for them.

Suggested male adjustment starting position.

Suggested female adjustment starting position.

These web sites have information that also might help you with fitting:

www.rei.com
The Perfect Fit - Bike Fit Basics

How to Fit a Bicycle by Peter Jon White